Esco | Downflow Booths

Pharmacon™ Downflow Booths

Downflow Booths provide containment by utilizing high velocity air to capture airborne dust particles. Downflow Booths are versatile devices that can:

Be used to control exposure risk to hazardous materials for a wide variety of equipment and processes.
When used correctly, provide Operator Exposure Levels (OEL's) ≤100 micrograms/meter3 over an 8 hour Time Weighted Average (TWA).
Enhance cGMP practices.

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Modular, easy-to-clean rigid design with minimal joints.
Single, Two-Stage or Three-Stage HEPA/ULPA filtration can be accommodated.
Removable bulkhead panels enable access to fine dust filter for service from inside the booth.
Re-circulatory Airflow or Single Pass Airflow if solvent or hazardous fumes are present in the process (may also require explosion proof electricals).
Cooling Coils can be fitted to offset heat gains in re-circulatory airflow systems.
HEPA/ULPA gel-seal downflow filters are replaceable from within the boot. Gel-seal is more reliable than conventional gasketed seals.
Voltage-compensating blower(s) ensure stable airflow.
Magnehelic gauges provide convenient and reliable means for monitoring booth airflow.
Booths ship knocked-down for site assembly.
Compact ceiling and rear plenums maximize usable work area while minimizing floor space.
IQ/OQ protocols available.
Energy-efficient tear-drop light fittings minimize airflow disruption.
Comprehensive factory and site acceptance tests include: filter integrity, particle count (air cleanliness), downflow velocity and uniformity, exhaust velocity/volume, containment zone verification, noise level, light intensity, temperature rise and electrical safety.
Containment performance verified according to the ISPE Good Practice Guide, Assessing the Particulate Containment Performance of Pharmaceutical Equipment.

Options

Bag-in bag-out filter housings for safe filter change.
Total exhaust airflow.
Built-in cooling coils to offset booth temperature rise.
Facia cavities for computers, screens, printers.
Front PVC strips.
Services such as N2, water, compressed air.
Network connections.
Containment screen for high-containment applications.
Integral equipment such as drum lifters.
Hazardous area applications.
Temp and humidity control systems.
Entry and exit airlocks.
Touchscreen and digital pressure alarms in lieu of switches and pressure gauges.

Project Process Flow

Project Lead Received
Initial Contact by Esco Technical Sales Engineer On-Site Visit to Determine Customer Needs.
First Proposal Submitted Complete With Submittal Drawings and Quote.
Follow Up Visit(s) and Refinement(s) to Requirements.
Final Proposal Submitted, Agremeent on Commercial Details.
Customer Issues Purchase Order.
Mechanical and Electrical Engineering at Esco.
Customer Approval of Design and Drawings.
Fabrication and Assembly.
Integration of Externally Sourced Equipment (If Required).
Factory Acceptance Test at Esco with Documentation.
Packaging and Transport.
Field Service Installation and Site Acceptance Test.

DFB CE Certificate

Brochure, English
pdf

French Guide
pdf

Product Summary
pdf

Vietnamese Product Summary

FEATURES

Modular, easy-to-clean rigid design with minimal joints.
Single, Two-Stage or Three-Stage HEPA/ULPA filtration can be accommodated.
Removable bulkhead panels enable access to fine dust filter for service from inside the booth.
Re-circulatory Airflow or Single Pass Airflow if solvent or hazardous fumes are present in the process (may also require explosion proof electricals).
Cooling Coils can be fitted to offset heat gains in re-circulatory airflow systems.
HEPA/ULPA gel-seal downflow filters are replaceable from within the boot. Gel-seal is more reliable than conventional gasketed seals.
Voltage-compensating blower(s) ensure stable airflow.
Magnehelic gauges provide convenient and reliable means for monitoring booth airflow.
Booths ship knocked-down for site assembly.
Compact ceiling and rear plenums maximize usable work area while minimizing floor space.
IQ/OQ protocols available.
Energy-efficient tear-drop light fittings minimize airflow disruption.
Comprehensive factory and site acceptance tests include: filter integrity, particle count (air cleanliness), downflow velocity and uniformity, exhaust velocity/volume, containment zone verification, noise level, light intensity, temperature rise and electrical safety.
Containment performance verified according to the ISPE Good Practice Guide, Assessing the Particulate Containment Performance of Pharmaceutical Equipment.

ACCESSORIES

Options

Bag-in bag-out filter housings for safe filter change.
Total exhaust airflow.
Built-in cooling coils to offset booth temperature rise.
Facia cavities for computers, screens, printers.
Front PVC strips.
Services such as N2, water, compressed air.
Network connections.
Containment screen for high-containment applications.
Integral equipment such as drum lifters.
Hazardous area applications.
Temp and humidity control systems.
Entry and exit airlocks.
Touchscreen and digital pressure alarms in lieu of switches and pressure gauges.

Project Process Flow

Project Lead Received
Initial Contact by Esco Technical Sales Engineer On-Site Visit to Determine Customer Needs.
First Proposal Submitted Complete With Submittal Drawings and Quote.
Follow Up Visit(s) and Refinement(s) to Requirements.
Final Proposal Submitted, Agremeent on Commercial Details.
Customer Issues Purchase Order.
Mechanical and Electrical Engineering at Esco.
Customer Approval of Design and Drawings.
Fabrication and Assembly.
Integration of Externally Sourced Equipment (If Required).
Factory Acceptance Test at Esco with Documentation.
Packaging and Transport.
Field Service Installation and Site Acceptance Test.